Pharm MOD 1 Discussion Group 1 During clinical, you argon charge to care for a client receiving morphine IV for affirm of postoperative pain. The clinical instructor has assigned you to pardon the followers: A) What are the major differences between narcotising agonists, hypnagogic agonists-antagonists, and soporific antagonists? Narcotic agonists are drugs that fight back with the opioid receptors end-to-end the body to piss analgesia, sedation, or euphoria. These drugs are highly habit-forming (p. 408). Narcotic agonists-antagonists react with some opioid receptor sites to stimulate body process and block opposite opioid receptor sites. These drugs are not as addictive as pure somnific agonists (p. 414). Narcotic antagonists, which deed to reverse the effectuate of narcotics, are used to treat narcotic overdose or to reverse unacceptable unbecoming do (p. 417). B) Describe the cure actions, indications, contraindications, the most common adver se reactions, and all told important(p) drug-drug interactions for a narcotic. The narcotic agonist act at precise opioid receptor sites in the CNS to bring analgesia, sedation, and a hotshot of well-being. They also are used as antitussives and as adjuncts to everyday anesthesia to produce rapid analgesia, sedation, and respiratory natural depression.
Indications for narcotic agonists include relief of exhausting acute or inveterate pain, preoperative medication, analgesia during anesthesia, and specific somebody indications, depending on the receptor proportion (p. 409). Narcotic agonists are contraindicated in the following condi tions: presence of cognise allergy to any n! arcotic agonist to avoid hypersensitivity reactions; play caused by toxic poisons because depression of GI legal action could haul to increased absorption and perniciousness; and after biliary mathematical process or surgical anastomoses because of the adverse effects associated with slowed GI activity due to narcotics. Oxycodone is classified as pregnancy category B, whereas all of the other...
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